Pediatric Bone Marrow Transplant for Leukemia (ALL, AML, CML) at Sheba Hospital- JCI accreditated and Top-10 Hospitals 2025 by Newsweek

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Pediatric Bone Marrow Transplant for Leukemia (ALL, AML, CML)
Sheba Medical Center – Personalized, Advanced Care for Children

At Sheba Medical Center, we understand that a diagnosis of leukemia in a child changes everything for a family. Our Pediatric Bone Marrow Transplant (BMT) program is designed to provide not only world-class medical care, but also reassurance, compassion, and hope at every step.

As one of the leading pediatric transplant centers globally, Sheba combines decades of experience with cutting-edge therapies to treat children with acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML) especially in high-risk or relapsed cases where transplant offers the best chance for cure.

When is a Bone Marrow Transplant Needed?

For many children, leukemia can be successfully treated with chemotherapy. However, in certain situations such as relapse, resistance to treatment, or high-risk disease, a bone marrow transplant becomes the most effective path forward.

A transplant replaces the child’s diseased bone marrow with healthy stem cells, allowing a new, functioning immune system to develop and fight the cancer.

A Personalized Approach to Every Child

No two children are the same and neither are their treatments. At Sheba, every case is carefully evaluated by a multidisciplinary team of pediatric hemato-oncology and transplant experts to determine the optimal timing, donor source, and treatment strategy.

Whenever possible, a matched sibling donor is preferred.
If a sibling match is not available, Sheba actively secures the best possible alternative donor through advanced matching technologies and international registries. These include:

Matched unrelated donors from global donor programs
Haploidentical (partial match) family donors, such as parents
Cord blood transplants

Our advanced HLA and molecular laboratories enable precise donor matching, ensuring both safety and the highest likelihood of success.

Advanced Transplant Techniques

Sheba is recognized for applying the most advanced transplant methods available today, including:

T-cell depletion and CD34+ selection to reduce complications and improve outcomes
Integration of CAR-T cell therapy prior to transplant in selected high-risk leukemia cases
Access to innovative clinical trials and emerging therapies

These technologies allow us to safely perform transplants even in complex or previously untreatable situations.

World-Class Outcomes

Sheba’s Pediatric BMT program consistently achieves outcomes that meet or exceed international standards:

ALL & AML (first or second remission): ~70–85% success rates
Improved outcomes in relapsed cases through integration of advanced cellular therapies
Strong long-term survival and quality of life for pediatric patients

Our experience, combined with continuous research and innovation, allows us to offer children the best possible chance for cure.

Care Beyond Treatment

A bone marrow transplant is not just a procedure, it is a journey. At Sheba, children are cared for in dedicated, highly protected environments with advanced infection control, while families receive continuous guidance, emotional support, and clear communication throughout the process.

From diagnosis through recovery and long-term follow-up, our team remains closely involved—ensuring that each child not only overcomes the disease, but also returns to a healthy and fulfilling life.

Why Families Choose Sheba
Leading pediatric transplant center with global recognition
Expertise in complex and high-risk leukemia cases
Ability to secure suitable donors—even without a family match
Integration of CAR-T and advanced cellular therapies
Multidisciplinary, patient-centered care
Dedicated international patient services for a smooth experience
A Message of Hope

At Sheba Medical Center, we believe every child deserves access to the most advanced treatments available—delivered with compassion, precision, and unwavering commitment.

For children facing leukemia, bone marrow transplantation at Sheba is not just a treatment option—it is a pathway toward healing, recovery, and a brighter future.

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